Feather Fingers
Holly Adamous
MSN, RN, FNP · 8+ years · injector & neurotoxin specialist
A light touch is intentional — injectables should soften expressions, not erase them.
Skin & Growth Factors
Salmon-DNA Skin Booster (PDRN)
PDRN / Rejuran — salmon-DNA polynucleotides driven into the skin via microneedling for repair, collagen, and glow. From $800.
4.9 rating from 364+ verified reviews
4.9 Google Rating
364+ verified reviews from real clients. Your confidence is our priority.
Licensed Providers
Every treatment performed by certified, experienced medical professionals.
Women-Owned
Founded and led by women committed to personalized aesthetic care.
Inclusive Care
LGBTQ+ friendly and transgender safespace. All are welcome.
The Treatment
Microneedling + PDRN explained
PDRN — polydeoxyribonucleotide — is a regenerative molecule made of polynucleotides derived from salmon DNA. It's the same active ingredient as the branded product Rejuran. Microneedling opens thousands of micro-channels in the skin; PDRN is then driven through those channels to support your skin's own repair pathways.
The pairing works on two fronts. The microneedling triggers the wound-healing cascade — new collagen, new elastin. The PDRN polynucleotides give that response a regenerative boost: they help stimulate collagen, support hydration, and calm inflammation. The result is an improvement in overall skin quality — fine lines, under-eye crepiness, dullness, and that lit-from-within glow.
PDRN is a skin-quality booster, not a filler — it doesn't add volume; it helps the skin repair and rejuvenate itself. Results build over a series, typically 3 sessions spaced about 3-4 weeks apart. Downtime is minimal: redness or flushing for 1-2 days, like a mild sunburn.
PDRN, in plain terms
PDRN = polydeoxyribonucleotide = salmon-DNA polynucleotides — the same regenerative active found in Rejuran. Driven into freshly microneedled skin, it supports tissue repair, collagen, and hydration while calming inflammation. A skin-quality treatment, best in a series.
Last updated: June 16, 2026
At a Glance
Microneedling + PDRN Treatment Details
- Duration
- ~60 minutes (includes numbing)
- Downtime
- Redness/flushing 1-2 days, like a mild sunburn
- Pain level
- Minimal-to-mild with topical numbing
- Active ingredient
- PDRN — salmon-DNA polynucleotides (Rejuran)
- Best as a
- Series — typically 3 sessions, ~3-4 weeks apart
- Targets
- Skin quality, fine lines, under-eye crepiness, dullness, glow
60
Minute Session
3
Sessions in a Series
1-2
Days of Redness
0
Volume Added (Not a Filler)
How It Works
Microneedling + PDRN explained
- 01
Prep + Numb
Skin cleansed. Topical anesthetic applied so the session stays comfortable — minimal-to-mild sensation.
- 02
Microneedle
The microneedling device passes over the face in sections, opening thousands of micro-channels and kicking off the wound-healing cascade.
- 03
Drive in PDRN
PDRN polynucleotides (salmon DNA — the active in Rejuran) are pressed into the fresh micro-channels, where they support tissue repair, collagen, and hydration.
- 04
Calm + Build
A soothing post-care step settles the skin. Over the following weeks — and across the series — repair signals build for improved tone, texture, and glow.
Day-of · What to expect
60 minutes, start to door.
The beats of a microneedling + PDRN session.
0:00
Arrive
Paperwork. Makeup removed. Pre-treatment photos.
0:10
Numb
Topical anesthetic applied. Time to take effect.
0:35
Prep
Anesthetic removed. PDRN polynucleotide serum prepared.
0:40
Treat
Microneedling across the face in sections, then PDRN driven in through the channels.
0:55
Calm
Soothing post-care applied. Skin looks flushed, feels refreshed.
0:58
Plan
Post-care reviewed. Next session scheduled ~3-4 weeks out.
1:00
Leave
Drive yourself. Redness fades in 1-2 days. Light makeup day 2.
Pricing
Microneedling + PDRN Pricing
- Microneedling + PDRN (Salmon DNA)Per session, 60 minutes — microneedling with PDRN polynucleotidesFrom $800
Pricing from GHL calendar. Series packages discussed at consult.
Client Results
What Our Skin Clients Say
★★★★★
I tried Skinvive injections at the Los Angeles location and my skin feels insanely smooth and hydrated. Not fake or puffy, just naturally glowy.
★★★★★
I love the nurse , Highly recommend to anyone looking for fillers Botox and skin treatments. I was so happy with my Botox and Morpheus8 results I came back for filler , my jaw is completely changed more defined and contoured. Thank you to the nurses and staff at skinsation!
★★★★★
I love this place! I get all my med spa stuff done here and my skin looks amazing! I love Naira, Jenny, Bia, Farah and Victoria!
★★★★★
Skinsation LA is absolutely my new go to medical spa! No pain, no bruising, and the experience was better than I could have imagined. The staff is incredibly friendly, and the energy in the office is so positive and welcoming. Their prices are much lower than my previous medspa in Beverly Hills without compromising on quality. I highly recommend this place for anyone looking for great results, excellent service, and reasonable pricing.
★★★★★
I can’t recommend Skinsation LA enough. Everyone there is so welcoming and facility is beautiful, modern and feet clean. The injector is an absolute perfectionist, so kind, and gentle. Her eye for symmetry is top notch. Always checking in to make sure I was comfortable. Very little to no bruising. The prices are very fair (almost generous ;). I never felt any extra services were being pushed on me. Will def be back and would recommend Skinsation LA to anyone. 100% Even for just a consultation.
★★★★★
I can’t say enough amazing things about Skinsation! From the moment you walk in, you’re greeted with the warmest welcome and the kind of care that makes you feel truly valued as a client. The space is spotless, beautiful, and has that calming, spa-like atmosphere that instantly puts you at ease.
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Tagged on Instagram by clients who shared their results with their audiences.
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Meet your injectors
The hands behind the work
The Fairy Injector
Farah Chahine
PA-C, MMS · 6+ years · precision injector
Every unit is placed with a plan for how your face actually moves — refined, subtle, patient-first.
Physician-owned. By design.
The doctor behind the practice
Founder · Owner
Dr. Lusanik Galustian
Founder · Owner · MD · Board-certified internist · Aesthetic medicine specialist
I trained as an internist before I trained in aesthetics. That order matters. It's why every plan we build at Skinsation starts with the patient — not the procedure.
FAQ
Microneedling + PDRN Questions
What is PDRN, and is it really made from salmon DNA?
Yes. PDRN stands for polydeoxyribonucleotide — a regenerative molecule made of purified DNA fragments (polynucleotides) sourced from salmon. These salmon-derived polynucleotides are biocompatible with human skin and are the same active ingredient found in the branded product Rejuran. PDRN works by supporting your skin's own repair pathways rather than adding volume.
What does adding PDRN to microneedling actually do?
Microneedling creates thousands of micro-channels in the skin and triggers your body's wound-healing response. Driving PDRN polynucleotides into those channels gives that response a regenerative boost — it helps stimulate collagen, supports hydration, and calms inflammation. The combination targets overall skin quality: fine lines, under-eye crepiness, dullness, and that lit-from-within glow. PDRN is a skin-quality booster, not a filler — it doesn't add volume.
Is microneedling with PDRN safe? I have a fish or shellfish allergy.
PDRN is generally well-tolerated, and the purification process removes most of the salmon protein, leaving the DNA fragments. Salmon is a fish, not a shellfish, so a shellfish allergy is not the same concern. That said, if you have any known fish allergy — or any allergy concern at all — flag it during your consultation so your provider can assess suitability before treatment. Your safety comes first.
How many sessions of microneedling with PDRN do I need?
Results build over a series. We typically recommend a course of 3 sessions spaced about 3-4 weeks apart, with improvements in skin quality, tone, and texture accumulating across the series. Your provider will tailor the plan to your skin at consultation.
What's the downtime like?
Minimal. Expect redness or flushing for about 1-2 days — similar to a mild sunburn. Most clients are comfortable with light makeup by day 2. Strict sun protection afterward is important while the skin recovers.
How much does microneedling with PDRN cost?
Microneedling with PDRN (salmon DNA) at Skinsation LA starts at $800 per session — a 60-minute treatment that includes numbing time. Because results build over a series, series packages are discussed at your consultation.
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