Yes. Botox (onabotulinumtoxinA) carries an FDA indication for severe underarm sweating in adults when topical agents have not managed it well enough, and Botox for hyperhidrosis is on the Botox menu at Skinsation LA in Los Angeles. Here is who the treatment is for, what the label says, how it differs from the Botox we use for lines, and how a visit goes.
Does Botox help with underarm sweating?
Our Instagram post opens with the line "Sweating is normal. Excessive sweating doesn't have to be." The clinical name for heavy underarm sweating is axillary hyperhidrosis, and Botox (onabotulinumtoxinA) carries an FDA indication for treatment of severe axillary hyperhidrosis that is inadequately managed by topical agents in adults. That indication is distinct from the BOTOX Cosmetic label, which covers glabellar lines, forehead lines, lateral canthal lines, and platysma bands.
The label describes BOTOX as "an acetylcholine release inhibitor and a neuromuscular blocking agent." In the post we put the underarm version in plainer words: "Botox for hyperhidrosis helps temporarily reduce underarm sweating by blocking the signals that activate sweat glands." Our Botox page lists it as an excessive-sweating treatment for the underarms, next to the facial areas we treat.
Who is Botox for hyperhidrosis for?
The label's wording is specific: adults with severe underarm sweating that has not been adequately managed by topical agents, which in plain terms means the antiperspirant route has already been tried. Our Botox page names excessive underarm sweating among the concerns Botox is for, and it also lists the situations where we do not treat: pregnancy or breastfeeding, a known allergy to botulinum toxin, an active skin infection at the injection sites, and neuromuscular disorders such as myasthenia gravis. Whether the treatment fits you is settled at a consultation.
Botox for hyperhidrosis is a prescription treatment. The statements on this page about the indication come from the FDA label; everything about how we run the treatment comes from our own Botox page, and your plan is set at an in-person assessment. — Dr. Lusanik Galustian, MD
Is it the same Botox we use for lines?
Not quite, and the difference matters for planning. BOTOX and BOTOX Cosmetic are labeled separately, and the potency units of one cannot be compared to or converted into units of the other, so the underarm indication is treated as its own FDA-labeled use rather than as a version of forehead Botox. In practice that means the dose is planned for the underarm, not borrowed from a facial map. Our Botox page lists a dosing note of 50 or more units per side for hyperhidrosis, next to the per-unit facial pricing, and it lists the current starting price for the underarm treatment. The exact amount for you is set by your provider at the visit.
What happens at the visit?
A Botox visit at Skinsation LA starts with a consultation: your provider talks through your goals and maps the treatment. Our Botox page describes the rest of the visit for every area we treat: ultra-fine needles, a quick pinch as most clients describe it, topical numbing cream available for sensitive areas, and 15 to 30 minutes in the chair. Our Botox aftercare page carries the general rules we give after any Botox visit, including not rubbing or massaging the treated area and skipping heavy exercise and alcohol for 24 hours; your provider tells you anything specific to the underarms before you leave.
How long does Botox for sweating last?
We do not print a number here, because the interval differs from person to person and the figure belongs in your chart, not in an article. What we can say is what our post says: the reduction is temporary, which means sweating returns as the effect wears off. The follow-up visit is where your provider reviews how long the first treatment held and when to plan the next one.
Sweating is normal. Excessive sweating doesn't have to be.
Who performs it
Botox at Skinsation LA is performed by Holly Adamous, MSN, RN, FNP and Farah Chahine, PA-C, MMS, with medical oversight from Dr. Galustian, our founder and medical director. For a broader walk-through of what Botox treats beyond lines, our Botox guide covers it. Our office is on San Vicente Boulevard in Carthay Circle, and we see Botox clients from across Los Angeles, Beverly Hills, and West Hollywood.
- What you have already tried. The FDA indication is written for sweating that topical agents have not managed well enough.
- Whether anything on the do-not-treat list applies, from pregnancy to a neuromuscular disorder.
- The dose for your underarms, planned on its own label rather than borrowed from a facial map.
- When to come back, so your provider can review how long the first treatment held.
- Botox carries an FDA indication for severe underarm sweating in adults that topical agents have not managed well enough.
- BOTOX and BOTOX Cosmetic are labeled separately, and their units are not interchangeable, so underarm treatment is planned on its own terms.
- Our Botox page lists Botox for hyperhidrosis as an underarm treatment, with a dosing note of 50 or more units per side and the current starting price.
- The reduction is temporary; timing is reviewed at your follow-up rather than printed here.
- Performed by Holly Adamous, MSN, RN, FNP, or Farah Chahine, PA-C, MMS, under Dr. Galustian's medical oversight.
Sources
The indication and labeling statements above come from the FDA prescribing information reviewed for this article: BOTOX (onabotulinumtoxinA), 2023, and BOTOX Cosmetic, 2024, both on DailyMed. Everything about how we run the treatment is from our own Botox and aftercare pages.
This article is general education, not medical advice, and individual results vary. Whether Botox for hyperhidrosis is right for you, and how it is dosed and timed, is decided at an in-person assessment. — Dr. Lusanik Galustian, MD
View this reel on Instagram
